Evaluation of Homocysteine Levels in Patients with Polycystic Ovarian Syndrome
نویسندگان
چکیده
BACKGROUND To determine the level of plasma homocysteine in patients with polycystic ovary syndrome (PCOS) compared with healthy controls. MATERIALS AND METHODS In this prospective case-control study on 85 PCOS women and 83 controls matched by body mass index (BMI), homocysteine levels were assessed. RESULTS The mean level of homocysteine was 16.25 ± 11.94 μmol/L in patients with PCOS and 11.58 ± 3.82 μmol/L in controls (p=0.002). Patients with PCOS had a significantly higher risk for hyperhomocysteinemia compared with BMI-matched control women. CONCLUSION These data suggest that homocysteine levels are elevated in the PCOS population. Further studies are needed to characterize this relationship.
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Introduction & Objective: Polycystic ovary syndrome (PCOS) is the most common endocrine disorder in women of reproductive age. According to the Rotterdam criteria, this syndrome is identified by presence of two of three criteria: (1) polycystic ovaries (2) oligo/anovulation and/or (3) clinical or biochemical evidence of hyperandrogenism. Low mature oocyte and embryo have been reported in poly...
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عنوان ژورنال:
دوره 4 شماره
صفحات -
تاریخ انتشار 2011